Assistant Professor

Research

The Innovative Approaches in Medicinal Chemistry research group is focused on the discovery of bioactive molecules with the aim of contributing to the investigation of biological processes and the development...

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dualsteric ligand

Dualsteric Ligands

Dualsteric (or bitopic) ligands represent a novel mode of targeting G protein-coupled receptors (GPCRs). These compounds attach simultaneously to the orthosteric binding site and an additional allosteric binding area of...

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nicotinic receptor

Nicotinic Acetylcholine Receptor Ligands

Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that mediate fast neurotransmission in the central and peripheral nervous systems. They are broadly distributed across the peripheral nervous system (PNS)...

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PET imaging

PET Radiotracers

Design and synthesis of cold precursors of radiotracers for positron emission tomography (PET) as putative diagnostic probes in preclinical phase for reaching the target, defining the stage of the disease,...

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photoswitchable ligand

Photopharmacology

“The Light Side of the Drugs” (semi-quote) Light is an unparalleled external signal to noninvasively manipulate biological systems with high spatial and temporal resolution. Photopharmacology relies on the use of...

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conceptual design of hybrid ligands

Polypharmacology

Polypharmacology refers to the development and the use of pharmaceutical agents that act on multiple targets or disease pathways. It is generally thought that complex diseases – such as central nervous...

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scheme of the project

Targeted Protein Degraders

Targeted protein degradation based on proteolysis-targeting chimeras (PROTACs) is a rapidly developing technology for the inhibition of protein function, via direct degradation mediated by ubiquitin-proteasome system. PROTACs are hetero-bifunctional small...

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microwave reactor

Equipment

Microwave reactor, flash chromatography, high-performance liquid chromatography, ...

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people network

Collaborations

Combining expertise and resources to answer bigger and more complex scientific questions and expand the breadth of our research

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Teaching

Corso di Laurea in Chimica e Tecnologia Farmaceutiche Corso di Laurea in Biotecnologia

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Contacts

We enjoy new interactions and value partnerships. If you wish to explore potential collaborations or would like to know more about what we do, please contact us: IAMedChem@unimi.it Department of...

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