N-8-Iper

Functionally selective and biased dualsteric agonist of muscarinic acetylcholine receptors

References

The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells

Novel analgesic agents obtained by molecular hybridization of orthosteric and allosteric ligands

Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling

Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor

Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor

Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling