P-6-Iper

Functionally selective and biased dualsteric agonist of muscarinic acetylcholine receptors

References

Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling

Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor

Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity