Stable Isotope Pharmacology

Stable isotopes, such as 13C, 2H, 18O, and 15N, are powerful tools in pharmacological research, advancing our understanding of biochemical processes and optimizing drug development. One of their key uses is in metabolic pathway studies, where they help track the movement and transformation of drugs within the body. They are also essential for pharmacokinetic analysis, allowing researchers to measure how a drug is absorbed, distributed, metabolized, and excreted (ADME). By integrating stable isotopes into drug molecules, scientists can gain a clearer understanding of their behavior in vivo.