Publications
(2015-to date)
| 1. | Synthesis, photochemical and biological evaluation of novel photoswitchable glycomimetic ligands of Pseudomonas aeruginosa LecB. Bhattacharya S, Tempra G, Colleoni A, Matera C, Castagna R, Parisini E.RSC Adv. 2025 Dec 12;15(58):49796-49808. doi: 10.1039/d5ra06897e. eCollection 2025 Dec 12.PMID: 41393209 |
| 2. | Photoswitching endogenous glutamate receptors in neural ensembles and single synapses in vivo. Garrido-Charles A, Bosch M, Lee H, Rovira X, Pittolo S, Llobet A, Wong HH, Trapero A, Matera C, Papotto C, Serra C, Llebaria A, Soriano E, Sanchez-Vives MV, Holt CE, Gorostiza P.Brain Stimul. 2025 Nov-Dec;18(6):1779-1793. doi: 10.1016/j.brs.2025.09.005. Epub 2025 Sep 11.PMID: 40945605 |
| 3. | Novel 3D-Printed Biophotonic Scaffold Displaying Luminescence under Near-Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release. Ghanavati S, Opar E, Gobbo VA, Matera C, Riefolo F, Castagna R, Colombelli J, Draganski A, Baggott J, Lastusaari M, Gorostiza P, Petit L, Massera J.Adv Healthc Mater. 2025 Aug 18:e02163. doi: 10.1002/adhm.202502163. Online ahead of print.PMID: 40820591 |
| 4. | Discovery of semisynthetic derivatives of (R)- and (S)-usnic acids as potential antifungal agents against C. tropicalisand T. rubrum. Fontana A, Colleoni A, Listro R, Rossino G, Linciano P, Vigani B, Valentino C, Cavalloro V, Temporiti MEE, Tosi S, Martino E, Collina S.RSC Med Chem. 2025 Jul 10;16(9):4390-4404. doi: 10.1039/d5md00457h. eCollection 2025 Sep 17.PMID: 40689027 |
| 5. | Effects of Selective α7 Nicotinic Acetylcholine Receptor Stimulation in Oligodendrocytes: Putative Implication in Neuroinflammation. Guerriero C, Puliatti G, Di Marino T, Scanavino G, Matera C, Dallanoce C, Tata AM.Cells. 2025 Jun 20;14(13):948. doi: 10.3390/cells14130948.PMID: 40643469 |
| 6. | Noninvasive cardiac modulation via triplet-sensitized photoswitching in the phototherapeutic window. Naimovičius L, Miroshnichenko M, Opar E, Hölzel H, Morikawa MA, Kimizuka N, Dapkevičius M, Lekavičius J, Radiunas E, Kazlauskas K, Cilleros-Mañé V, Riefolo F, Matera C, Harmandar K, Taniguchi M, Dumoulin F, Lindsey JS, Bharmoria P, Gorostiza P, Moth-Poulsen K.Nat Commun. 2025 Jul 10;16(1):6377. doi: 10.1038/s41467-025-61301-3.PMID: 40640135 |
| 7. | Expanding the P2X7R toolbox: discovery of a novel Iodine-125 radioligand. Tempra G, Matera C.Purinergic Signal. 2025 May 9. doi: 10.1007/s11302-025-10094-7. Online ahead of print.PMID: 40343548 |
| 8. | Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light. Maleeva G, Matera C, Roda S, Colleoni A, De Amici M, Gorostiza P.Med Res Rev. 2025 Sep;45(5):1407-1422. doi: 10.1002/med.22112. Epub 2025 Apr 10.PMID: 40211663 Review. |
| 9. | Discotic amphiphilic supramolecular polymers for drug release and cell activation with light. Santini R, Fuentes E, Maleeva G, Matera C, Riefolo F, Berrocal JA, Albertazzi L, Gorostiza P, Pujals S.Nanoscale. 2025 May 2;17(17):10985-10995. doi: 10.1039/d4nr02957g.PMID: 40202720 |
| 10. | Light-Activated Pharmacological Tools for Exploring the Cholinergic System. Colleoni A, Galli G, Dallanoce C, De Amici M, Gorostiza P, Matera C.Med Res Rev. 2025 Jul;45(4):1251-1274. doi: 10.1002/med.22108. Epub 2025 Mar 23.PMID: 40123150 Review. |
| 11. | Control of cortical slow oscillations and epileptiform discharges with photoswitchable type 1 muscarinic ligands. Sanchez-Sanchez JM, Riefolo F, Barbero-Castillo A, Sortino R, Agnetta L, Manasanch A, Matera C, Bosch M, Forcella M, Decker M, Gorostiza P, Sanchez-Vives MV.PNAS Nexus. 2025 Jan 15;4(2):pgaf009. doi: 10.1093/pnasnexus/pgaf009. eCollection 2025 Feb.PMID: 40007579 |
| 12. | Sulfonium Moieties as Ammonium Bioisosteres: Novel Ligands for the Alpha7 Nicotinic Acetylcholine Receptor. Papotto C, Stokes C, Matera C, Herz SM, Chiang K, Ferrisi R, De Amici M, Damaj MI, Papke RL, Dallanoce C.J Med Chem. 2025 Feb 13;68(3):3157-3179. doi: 10.1021/acs.jmedchem.4c02399. Epub 2025 Jan 20.PMID: 39829331 |
| 13. | Novel Orthosteric/Allosteric Ligands of Cannabinoid Receptors: An Unexpected Pharmacological Profile. Ferrisi R, Polini B, Smolyakova AM, Migone C, Giammattei G, Banti M, Baron G, Della Vedova L, Chiellini G, Gado F, Piras AM, Rapposelli S, Laprairie RB, Ortore G, Manera C.J Med Chem. 2025 Jan 23;68(2):1280-1299. doi: 10.1021/acs.jmedchem.4c01778. Epub 2025 Jan 3.PMID: 39749716 |
| 14. | 1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration. Listro R, Rossino G, Cavalloro V, Rossi D, Boiocchi M, Robescu MS, Bavaro T, Franchini S, Sorbi C, De Amici M, Linciano P, Collina S.Int J Mol Sci. 2024 Nov 29;25(23):12880. doi: 10.3390/ijms252312880.PMID: 39684589 |
| 15. | Histidine containing dipeptides protect epithelial and endothelial cell barriers from methylglyoxal induced injury. Wetzel C, Gallenstein N, Peters V, Fleming T, Marinovic I, Bodenschatz A, Du Z, Küper K, Dallanoce C, Aldini G, Schmoch T, Brenner T, Weigand MA, Zarogiannis SG, Schmitt CP, Bartosova M.Sci Rep. 2024 Nov 4;14(1):26640. doi: 10.1038/s41598-024-77891-9.PMID: 39496731 |
| 16. | A Photoactivatable Version of Ivabradine Enables Light-Induced Block of HCN Current In Vivo. Porro A, Armano E, Brandalise F, Appiani R, Beltrame M, Saponaro A, Dallanoce C, Nakajo K, Ryu K, Leone R, Thiel G, Pallavicini M, Moroni A, Bolchi C.J Med Chem. 2024 Sep 26;67(18):16209-16221. doi: 10.1021/acs.jmedchem.4c01047. Epub 2024 Sep 5.PMID: 39238314 |
| 17. | In vivo photocontrol of orexin receptors with a nanomolar light-regulated analogue of orexin-B. Prischich D, Sortino R, Gomila-Juaneda A, Matera C, Guardiola S, Nepomuceno D, Varese M, Bonaventure P, de Lecea L, Giralt E, Gorostiza P.Cell Mol Life Sci. 2024 Jul 6;81(1):288. doi: 10.1007/s00018-024-05308-x.PMID: 38970689 |
| 18. | Photoswitchable Carbamazepine Analogs for Non-Invasive Neuroinhibition In Vivo. Camerin L, Maleeva G, Gomila AMJ, Suárez-Pereira I, Matera C, Prischich D, Opar E, Riefolo F, Berrocoso E, Gorostiza P.Angew Chem Int Ed Engl. 2024 Sep 16;63(38):e202403636. doi: 10.1002/anie.202403636. Epub 2024 Aug 14.PMID: 38887153 |
| 19. | A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells.Polini B, Zallocco L, Gado F, Ferrisi R, Ricardi C, Zuccarini M, Carnicelli V, Manera C, Ronci M, Lucacchini A, Zucchi R, Giusti L, Chiellini G.Cells. 2024 May 19;13(10):875. doi: 10.3390/cells13100875.PMID: 38786097 |
| 20. | New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold. Dallanoce C, Richter K, Stokes C, Papotto C, Andleeb H, Thakur GA, Kerr A, Grau V, Papke RL.ACS Chem Neurosci. 2024 Feb 21;15(4):827-843. doi: 10.1021/acschemneuro.3c00720. Epub 2024 Feb 9.PMID: 38335726 |
| 21. | Gaucher Disease: A Glance from a Medicinal Chemistry Perspective. Prencipe F, Barzan C, Savian C, Spalluto G, Carosati E, De Amici M, Mosconi G, Gianferrara T, Federico S, Da Ros T.ChemMedChem. 2024 May 17;19(10):e202300641. doi: 10.1002/cmdc.202300641. Epub 2024 Mar 8.PMID: 38329692 Review. |
| 22. | M2 Muscarinic Receptor Stimulation Induces Autophagy in Human Glioblastoma Cancer Stem Cells via mTOR Complex-1 Inhibition. Guerriero C, Manfredelli M, Matera C, Iuzzolino A, Conti L, Dallanoce C, De Amici M, Trisciuoglio D, Tata AM.Cancers (Basel). 2023 Dec 20;16(1):25. doi: 10.3390/cancers16010025.PMID: 38201453 |
| 23. | Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers.Listro R, Marra A, Cavalloro V, Rossino G, Linciano P, Rossi D, Casali E, De Amici M, Mazzeo G, Longhi G, Fusè M, Dondio G, Pellavio G, Laforenza U, Schepmann D, Wünsch B, Collina S.J Pharm Biomed Anal. 2024 Feb 15;239:115902. doi: 10.1016/j.jpba.2023.115902. Epub 2023 Dec 14.PMID: 38101238 |
| 24. | The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer’s Disease. Ferrisi R, Gado F, Ricardi C, Polini B, Manera C, Chiellini G.J Clin Med. 2023 Nov 21;12(23):7201. doi: 10.3390/jcm12237201.PMID: 38068253 Review. |
| 25. | Three-Photon Infrared Stimulation of Endogenous Neuroreceptors in Vivo. Sortino R, Cunquero M, Castro-Olvera G, Gelabert R, Moreno M, Riefolo F, Matera C, Fernàndez-Castillo N, Agnetta L, Decker M, Lluch JM, Hernando J, Loza-Alvarez P, Gorostiza P.Angew Chem Int Ed Engl. 2023 Dec 18;62(51):e202311181. doi: 10.1002/anie.202311181. Epub 2023 Nov 20.PMID: 37823736 |
| 26. | Advances in small molecule selective ligands for heteromeric nicotinic acetylcholine receptors. Matera C, Papotto C, Dallanoce C, De Amici M.Pharmacol Res. 2023 Aug;194:106813. doi: 10.1016/j.phrs.2023.106813. Epub 2023 Jun 10.PMID: 37302724 Review. |
| 27. | α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways. Botticelli E, Guerriero C, Fucile S, De Stefano ME, Matera C, Dallanoce C, De Amici M, Tata AM.Cells. 2023 May 28;12(11):1494. doi: 10.3390/cells12111494.PMID: 37296615 |
| 28. | Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation.Matera C, Kauk M, Cirillo D, Maspero M, Papotto C, Volpato D, Holzgrabe U, De Amici M, Hoffmann C, Dallanoce C.Molecules. 2023 Mar 6;28(5):2407. doi: 10.3390/molecules28052407.PMID: 36903650 |
| 29. | Dual Cannabinoid and Orexin Regulation of Anhedonic Behaviour Caused by Prolonged Restraint Stress. Kim HJJ, Zagzoog A, Ceni C, Ferrisi R, Janz N, Laprairie RB.Brain Sci. 2023 Feb 13;13(2):314. doi: 10.3390/brainsci13020314.PMID: 36831860 |
| 30. | New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2. Ferrisi R, Polini B, Ricardi C, Gado F, Mohamed KA, Baron G, Faiella S, Poli G, Rapposelli S, Saccomanni G, Aldini G, Chiellini G, Laprairie RB, Manera C, Ortore G.Int J Mol Sci. 2023 Jan 21;24(3):2135. doi: 10.3390/ijms24032135.PMID: 36768458 |
| 31. | Light-Controlled Modulation and Analysis of Neuronal Functions. Matera C, Bregestovski P.Int J Mol Sci. 2022 Oct 26;23(21):12921. doi: 10.3390/ijms232112921.PMID: 36361710 |
| 32. | Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R).Ferrisi R, Gado F, Polini B, Ricardi C, Mohamed KA, Stevenson LA, Ortore G, Rapposelli S, Saccomanni G, Pertwee RG, Laprairie RB, Manera C, Chiellini G.Front Chem. 2022 Sep 27;10:984069. doi: 10.3389/fchem.2022.984069. eCollection 2022.PMID: 36238097 |
| 33. | Recent Advances in the Modulation of Cholinergic Signaling. Dallanoce C.Molecules. 2022 Sep 14;27(18):5971. doi: 10.3390/molecules27185971.PMID: 36144707 |
| 34. | Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals. Matera C, Calvé P, Casadó-Anguera V, Sortino R, Gomila AMJ, Moreno E, Gener T, Delgado-Sallent C, Nebot P, Costazza D, Conde-Berriozabal S, Masana M, Hernando J, Casadó V, Puig MV, Gorostiza P.Int J Mol Sci. 2022 Sep 4;23(17):10114. doi: 10.3390/ijms231710114.PMID: 36077512 |
| 35. | Donor-Acceptor Stenhouse Adduct Displaying Reversible Photoswitching in Water and Neuronal Activity. Castagna R, Maleeva G, Pirovano D, Matera C, Gorostiza P.J Am Chem Soc. 2022 Aug 31;144(34):15595-15602. doi: 10.1021/jacs.2c04920. Epub 2022 Aug 17.PMID: 35976640 |
| 36. | Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands.Gado F, Ferrisi R, Polini B, Mohamed KA, Ricardi C, Lucarini E, Carpi S, Domenichini F, Stevenson LA, Rapposelli S, Saccomanni G, Nieri P, Ortore G, Pertwee RG, Ghelardini C, Di Cesare Mannelli L, Chiellini G, Laprairie RB, Manera C.J Med Chem. 2022 Jul 28;65(14):9918-9938. doi: 10.1021/acs.jmedchem.2c00582. Epub 2022 Jul 18.PMID: 35849804 |
| 37. | Fast Photoswitchable Molecular Prosthetics Control Neuronal Activity in the Cochlea. Garrido-Charles A, Huet A, Matera C, Thirumalai A, Hernando J, Llebaria A, Moser T, Gorostiza P.J Am Chem Soc. 2022 Jun 1;144(21):9229-9239. doi: 10.1021/jacs.1c12314. Epub 2022 May 18.PMID: 35584208 |
| 38. | Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells.Gado F, Ferrisi R, Di Somma S, Napolitano F, Mohamed KA, Stevenson LA, Rapposelli S, Saccomanni G, Portella G, Pertwee RG, Laprairie RB, Malfitano AM, Manera C.Molecules. 2022 May 7;27(9):3019. doi: 10.3390/molecules27093019.PMID: 35566369 |
| 39. | The Exception That Proves the Rule: How Sodium Chelation Can Alter the Charge-Cell Binding Correlation of Fluorescein-Based Multimodal Imaging Agents.Maspero M, Dallanoce C, Wängler B, Wängler C, Hübner R.ChemMedChem. 2022 Apr 20;17(8):e202100739. doi: 10.1002/cmdc.202100739. Epub 2022 Feb 22.PMID: 35137522 |
| 40. | The Mechanisms Mediated by α7 Acetylcholine Nicotinic Receptors May Contribute to Peripheral Nerve Regeneration. Salazar Intriago MS, Piovesana R, Matera A, Taggi M, Canipari R, Fabrizi C, Papotto C, Matera C, De Amici M, Dallanoce C, Tata AM.Molecules. 2021 Dec 18;26(24):7668. doi: 10.3390/molecules26247668.PMID: 34946750 |
| 41. | CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators.Gado F, Ceni C, Ferrisi R, Sbrana G, Stevenson LA, Macchia M, Pertwee RG, Bertini S, Manera C, Ortore G.Eur J Pharm Sci. 2022 Feb 1;169:106088. doi: 10.1016/j.ejps.2021.106088. Epub 2021 Dec 1.PMID: 34863873 |
| 42. | The Role of Cannabinoids in Bone Metabolism: A New Perspective for Bone Disorders. Saponaro F, Ferrisi R, Gado F, Polini B, Saba A, Manera C, Chiellini G.Int J Mol Sci. 2021 Nov 16;22(22):12374. doi: 10.3390/ijms222212374.PMID: 34830256 Review. |
| 43. | Synthesis, Characterization and In Vitro Evaluation of Hybrid Monomeric Peptides Suited for Multimodal Imaging by PET/OI: Extending the Concept of Charge-Cell Binding Correlation.Maspero M, Cheng X, von Kiedrowski V, Dallanoce C, Wängler B, Hübner R, Wängler C.Pharmaceuticals (Basel). 2021 Sep 28;14(10):989. doi: 10.3390/ph14100989.PMID: 34681213 |
| 44. | Synthesis and characterization of 13C labeled carnosine derivatives for isotope dilution mass spectrometry measurements in biological matrices.Maspero M, Gilardoni E, Bonfanti C, Messina G, Regazzoni L, De Amici M, Carini M, Aldini G, Dallanoce C.Talanta. 2021 Dec 1;235:122742. doi: 10.1016/j.talanta.2021.122742. Epub 2021 Jul 26.PMID: 34517610 |
| 45. | The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells.Guerriero C, Matera C, Del Bufalo D, De Amici M, Conti L, Dallanoce C, Tata AM.Cells. 2021 Jul 24;10(8):1877. doi: 10.3390/cells10081877.PMID: 34440646 |
| 46. | PESIN Conjugates for Multimodal Imaging: Can Multimerization Compensate Charge Influences on Cell Binding Properties? A Case Study.Hübner R, Paretzki A, von Kiedrowski V, Maspero M, Cheng X, Davarci G, Braun D, Damerow H, Judmann B, Filippou V, Dallanoce C, Schirrmacher R, Wängler B, Wängler C.Pharmaceuticals (Basel). 2021 Jun 2;14(6):531. doi: 10.3390/ph14060531.PMID: 34199635 |
| 47. | Rational Design of Photochromic Analogues of Tricyclic Drugs. Riefolo F, Sortino R, Matera C, Claro E, Preda B, Vitiello S, Traserra S, Jiménez M, Gorostiza P.J Med Chem. 2021 Jul 8;64(13):9259-9270. doi: 10.1021/acs.jmedchem.1c00504. Epub 2021 Jun 23.PMID: 34160229 |
| 48. | Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB2R modulators in neurodegenerative diseases.Ferrisi R, Ceni C, Bertini S, Macchia M, Manera C, Gado F.Pharmacol Res. 2021 Aug;170:105607. doi: 10.1016/j.phrs.2021.105607. Epub 2021 Jun 3.PMID: 34089867 Review. |
| 49. | Control of Brain State Transitions with a Photoswitchable Muscarinic Agonist. Barbero-Castillo A, Riefolo F, Matera C, Caldas-Martínez S, Mateos-Aparicio P, Weinert JF, Garrido-Charles A, Claro E, Sanchez-Vives MV, Gorostiza P.Adv Sci (Weinh). 2021 Jul;8(14):e2005027. doi: 10.1002/advs.202005027. Epub 2021 May 21.PMID: 34018704 |
| 50. | Stable desensitization of α7 nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site.Pismataro MC, Horenstein NA, Stokes C, Dallanoce C, Thakur GA, Papke RL.Eur J Pharmacol. 2021 Aug 15;905:174179. doi: 10.1016/j.ejphar.2021.174179. Epub 2021 May 15.PMID: 34004208 |
| 51. | Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor.Gado F, Mohamed KA, Meini S, Ferrisi R, Bertini S, Digiacomo M, D’Andrea F, Stevenson LA, Laprairie RB, Pertwee RG, Manera C.Eur J Med Chem. 2021 Feb 5;211:113116. doi: 10.1016/j.ejmech.2020.113116. Epub 2020 Dec 25.PMID: 33360803 |
| 52. | 2020 Italian Special Anniversary Collection: Celebrating NMMC 2019 and 40 Years of the DCF-SCI. Carini M, De Amici M.ChemMedChem. 2021 Jan 19;16(2):303-308. doi: 10.1002/cmdc.202000926. Epub 2020 Dec 23.PMID: 33354905 |
| 53. | Effects mediated by the α7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells. Pernarella M, Piovesana R, Matera C, Faroni A, Fiore M, Dini L, Reid AJ, Dallanoce C, Tata AM.Eur J Histochem. 2020 Oct 30;64(s2):3159. doi: 10.4081/ejh.2020.3159.PMID: 33334089 |
| 54. | Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist.Polini B, Cervetto C, Carpi S, Pelassa S, Gado F, Ferrisi R, Bertini S, Nieri P, Marcoli M, Manera C.Life (Basel). 2020 Dec 8;10(12):333. doi: 10.3390/life10120333.PMID: 33302569 |
| 55. | Adrenergic Modulation With Photochromic Ligands.Prischich D, Gomila AMJ, Milla-Navarro S, Sangüesa G, Diez-Alarcia R, Preda B, Matera C, Batlle M, Ramírez L, Giralt E, Hernando J, Guasch E, Meana JJ, de la Villa P, Gorostiza P.Angew Chem Int Ed Engl. 2021 Feb 15;60(7):3625-3631. doi: 10.1002/anie.202010553. Epub 2020 Dec 21.PMID: 33103317 |
| 56. | Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling. Holze J, Bermudez M, Pfeil EM, Kauk M, Bödefeld T, Irmen M, Matera C, Dallanoce C, De Amici M, Holzgrabe U, König GM, Tränkle C, Wolber G, Schrage R, Mohr K, Hoffmann C, Kostenis E, Bock A.ACS Pharmacol Transl Sci. 2020 Sep 2;3(5):859-867. doi: 10.1021/acsptsci.0c00069. eCollection 2020 Oct 9.PMID: 33073186 |
| 57. | Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.Granchi C, Bononi G, Ferrisi R, Gori E, Mantini G, Glasmacher S, Poli G, Palazzolo S, Caligiuri I, Rizzolio F, Canzonieri V, Perin T, Gertsch J, Sodi A, Giovannetti E, Macchia M, Minutolo F, Tuccinardi T, Chicca A.Eur J Med Chem. 2021 Jan 1;209:112857. doi: 10.1016/j.ejmech.2020.112857. Epub 2020 Oct 7.PMID: 33045662 |
| 58. | Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation.Pismataro MC, Horenstein NA, Stokes C, Quadri M, De Amici M, Papke RL, Dallanoce C.Eur J Med Chem. 2020 Nov 1;205:112669. doi: 10.1016/j.ejmech.2020.112669. Epub 2020 Jul 28.PMID: 32810771 |
| 59. | Development of a direct LC-ESI-MS method for the measurement of human serum carnosinase activity. Gilardoni E, Gervasoni S, Maspero M, Dallanoce C, Vistoli G, Carini M, Aldini G, Regazzoni L.J Pharm Biomed Anal. 2020 Sep 10;189:113440. doi: 10.1016/j.jpba.2020.113440. Epub 2020 Jun 22.PMID: 32645617 |
| 60. | An Azobenzene-Based Single-Component Supramolecular Polymer Responsive to Multiple Stimuli in Water. Fuentes E, Gerth M, Berrocal JA, Matera C, Gorostiza P, Voets IK, Pujals S, Albertazzi L.J Am Chem Soc. 2020 Jun 3;142(22):10069-10078. doi: 10.1021/jacs.0c02067. Epub 2020 May 26.PMID: 32395995 |
| 61. | Novel analgesic agents obtained by molecular hybridization of orthosteric and allosteric ligands. Matera C, Flammini L, Riefolo F, Domenichini G, De Amici M, Barocelli E, Dallanoce C, Bertoni S.Eur J Pharmacol. 2020 Jun 5;876:173061. doi: 10.1016/j.ejphar.2020.173061. Epub 2020 Mar 13.PMID: 32179086 |
| 62. | Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study. Vistoli G, Aldini G, Fumagalli L, Dallanoce C, Angeli A, Supuran CT.Int J Mol Sci. 2020 Mar 4;21(5):1761. doi: 10.3390/ijms21051761.PMID: 32143488 |
| 63. | Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors.Maspero M, Volpato D, Cirillo D, Yuan Chen N, Messerer R, Sotriffer C, De Amici M, Holzgrabe U, Dallanoce C.Bioorg Chem. 2020 Mar;96:103633. doi: 10.1016/j.bioorg.2020.103633. Epub 2020 Jan 30.PMID: 32032848 |
| 64. | Optical Control of Cardiac Function with a Photoswitchable Muscarinic Agonist. Riefolo F, Matera C, Garrido-Charles A, Gomila AMJ, Sortino R, Agnetta L, Claro E, Masgrau R, Holzgrabe U, Batlle M, Decker M, Guasch E, Gorostiza P.J Am Chem Soc. 2019 May 8;141(18):7628-7636. doi: 10.1021/jacs.9b03505. Epub 2019 Apr 26.PMID: 31010281 |
| 65. | Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. Agnetta L, Bermudez M, Riefolo F, Matera C, Claro E, Messerer R, Littmann T, Wolber G, Holzgrabe U, Decker M.J Med Chem. 2019 Mar 28;62(6):3009-3020. doi: 10.1021/acs.jmedchem.8b01822. Epub 2019 Mar 19.PMID: 30827105 |
| 66. | The novel hybrid agonist HyNDA-1 targets the D3R-nAChR heteromeric complex in dopaminergic neurons. Matera C, Bono F, Pelucchi S, Collo G, Bontempi L, Gotti C, Zoli M, De Amici M, Missale C, Fiorentini C, Dallanoce C.Biochem Pharmacol. 2019 May;163:154-168. doi: 10.1016/j.bcp.2019.02.019. Epub 2019 Feb 14.PMID: 30772268 |
| 67. | Photoswitchable Antimetabolite for Targeted Photoactivated Chemotherapy. Matera C, Gomila AMJ, Camarero N, Libergoli M, Soler C, Gorostiza P.J Am Chem Soc. 2018 Nov 21;140(46):15764-15773. doi: 10.1021/jacs.8b08249. Epub 2018 Oct 22.PMID: 30346152 |
| 68. | Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation.Quadri M, Silnović A, Matera C, Horenstein NA, Stokes C, De Amici M, Papke RL, Dallanoce C.Eur J Med Chem. 2018 Dec 5;160:207-228. doi: 10.1016/j.ejmech.2018.10.015. Epub 2018 Oct 11.PMID: 30342362 |
| 69. | A Small Library of 1,2,3-Triazole Analogs of CAP-55: Synthesis and Binding Affinity at Nicotinic Acetylcholine Receptors. Rizzi L, Gotti C, De Amici M, Dallanoce C, Matera C.Chem Biodivers. 2018 Sep;15(9):e1800210. doi: 10.1002/cbdv.201800210. Epub 2018 Jul 27.PMID: 29953725 |
| 70. | Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells.Cristofaro I, Spinello Z, Matera C, Fiore M, Conti L, De Amici M, Dallanoce C, Tata AM.Neurochem Int. 2018 Sep;118:52-60. doi: 10.1016/j.neuint.2018.04.010. Epub 2018 Apr 24.PMID: 29702145 |
| 71. | In vivo and in vitro ADMET profiling and in vivo pharmacodynamic investigations of a selective α7 nicotinic acetylcholine receptor agonist with a spirocyclic Δ2-isoxazoline molecular skeleton.Matera C, Dondio G, Braida D, Ponzoni L, De Amici M, Sala M, Dallanoce C.Eur J Pharmacol. 2018 Feb 5;820:265-273. doi: 10.1016/j.ejphar.2017.12.047. Epub 2017 Dec 21.PMID: 29275158 |
| 72. | Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation.Quadri M, Matera C, Silnović A, Pismataro MC, Horenstein NA, Stokes C, Papke RL, Dallanoce C.ChemMedChem. 2017 Aug 22;12(16):1335-1348. doi: 10.1002/cmdc.201700162. Epub 2017 Jun 12.PMID: 28494140 |
| 73. | Novel bipharmacophoric inhibitors of the cholinesterases with affinity to the muscarinic receptors M1 and M2. Messerer R, Dallanoce C, Matera C, Wehle S, Flammini L, Chirinda B, Bock A, Irmen M, Tränkle C, Barocelli E, Decker M, Sotriffer C, De Amici M, Holzgrabe U.Medchemcomm. 2017 Apr 27;8(6):1346-1359. doi: 10.1039/c7md00149e. eCollection 2017 Jun 1.PMID: 30108847 |
| 74. | A New Molecular Mechanism To Engineer Protean Agonism at a G Protein-Coupled Receptor. De Min A, Matera C, Bock A, Holze J, Kloeckner J, Muth M, Traenkle C, De Amici M, Kenakin T, Holzgrabe U, Dallanoce C, Kostenis E, Mohr K, Schrage R.Mol Pharmacol. 2017 Apr;91(4):348-356. doi: 10.1124/mol.116.107276. Epub 2017 Feb 6.PMID: 28167741 |
| 75. | Engineered Context-Sensitive Agonism: Tissue-Selective Drug Signaling through a G Protein-Coupled Receptor. Seemann WK, Wenzel D, Schrage R, Etscheid J, Bödefeld T, Bartol A, Warnken M, Sasse P, Klöckner J, Holzgrabe U, DeAmici M, Schlicker E, Racké K, Kostenis E, Meyer R, Fleischmann BK, Mohr K.J Pharmacol Exp Ther. 2017 Feb;360(2):289-299. doi: 10.1124/jpet.116.237149. Epub 2016 Nov 15.PMID: 28082514 |
| 76. | In vivo study of the role of α6-containing nicotinic acetylcholine receptor in retinal function using subtype-specific RDP-MII(E11R) toxin.Barloscio D, Cerri E, Domenici L, Longhi R, Dallanoce C, Moretti M, Vilella A, Zoli M, Gotti C, Origlia N.FASEB J. 2017 Jan;31(1):192-202. doi: 10.1096/fj.201600855R. Epub 2016 Sep 28.PMID: 27682206 |
| 77. | Insight into the Mechanism of Hydrolysis of Meropenem by OXA-23 Serine-β-lactamase Gained by Quantum Mechanics/Molecular Mechanics Calculations.Sgrignani J, Grazioso G, De Amici M.Biochemistry. 2016 Sep 13;55(36):5191-200. doi: 10.1021/acs.biochem.6b00461. Epub 2016 Aug 31.PMID: 27534275 |
| 78. | Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor. Bock A, Bermudez M, Krebs F, Matera C, Chirinda B, Sydow D, Dallanoce C, Holzgrabe U, De Amici M, Lohse MJ, Wolber G, Mohr K.J Biol Chem. 2016 Jul 29;291(31):16375-89. doi: 10.1074/jbc.M116.735431. Epub 2016 Jun 13.PMID: 27298318 |
| 79. | Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype.Matera C, Quadri M, Sciaccaluga M, Pomè DY, Fasoli F, De Amici M, Fucile S, Gotti C, Dallanoce C, Grazioso G.Eur J Med Chem. 2016 Jan 27;108:392-405. doi: 10.1016/j.ejmech.2015.11.045. Epub 2015 Dec 5.PMID: 26706350 |
| 80. | Allosteric Modulation of Alpha7 Nicotinic Receptors: Mechanistic Insight through Metadynamics and Essential Dynamics. Grazioso G, Sgrignani J, Capelli R, Matera C, Dallanoce C, De Amici M, Cavalli A.J Chem Inf Model. 2015 Dec 28;55(12):2528-39. doi: 10.1021/acs.jcim.5b00459. Epub 2015 Nov 20.PMID: 26569022 |
| 81. | Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization. Matera C, Pucci L, Fiorentini C, Fucile S, Missale C, Grazioso G, Clementi F, Zoli M, De Amici M, Gotti C, Dallanoce C.Eur J Med Chem. 2015 Aug 28;101:367-83. doi: 10.1016/j.ejmech.2015.06.039. Epub 2015 Jun 20.PMID: 26164842 |
| 82. | On the selection of an opioid for local skin analgesia: Structure-skin permeability relationships. Musazzi UM, Matera C, Dallanoce C, Vacondio F, De Amici M, Vistoli G, Cilurzo F, Minghetti P.Int J Pharm. 2015 Jul 15;489(1-2):177-85. doi: 10.1016/j.ijpharm.2015.04.071. Epub 2015 Apr 28.PMID: 25934430 |